All of the above apply to Neuroma with a few exceptions. Most patients with a Neuroma relate fairly immediate relief with strappings and custom orthotics. In those that do not see this significant improvement early on, the argument for UltraCryo is compelling. More than 80% of patients undergoing the procedure for Neuroma symptoms relate more than 80% relief within hours to days of having the procedure done. The other significant exception is that having the procedure done allows the patient to spend less time in their orthotics. This is very important to women who are required to wear dressy shoes and higher heeled pumps to work and can only wear their orthotics in the evenings and weekends. The UltraCryo provides immediate relief and sustained relief with less frequent orthotics wear.